Analysis of the optic nerve head microcirculation using OCT-A and the upstream macrocirculation using CDI in low- and high-tension glaucoma patients

Introduction: To analyze the optic nerve head (ONH) microcirculation using optical coherence tomography angiography (OCT-A) and the upstream macrocirculation using color Doppler imaging (CDI) in low-tension and high-tension glaucoma (LTG and HTG, respectively). Methods: This cross-sectional study included 67 eyes of 67 HTG patients, 55 eyes of 55 LTG patients, and 42 eyes of 42 healthy controls. We recorded the complete ophthalmological examination, visual fields, retinal nerve fiber layer (RNFL) thickness, ONH vessel density (VD) measured using OCT-A, peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI) measured using CDI. SPSS software was used for data analysis. Data are presented as mean ± standard deviation or median (interquartile range) and compared using t-test or Mann-Whitney U test, as appropriate. Pearson chi-square test or Fisher’s exact test was used for comparisons, as appropriate. Pearson correlation analysis was used to evaluate for the correlations between variables. P
Source: Ophthalmic Research - Category: Opthalmology Source Type: research