Increased copy number of imprinted genes in the chromosomal region 20q11-q13.32 is associated with resistance to antitumor agents in cancer cell lines
Parent of origin-specific allelic expression of imprinted genes is epigenetically controlled. In cancer, imprinted genes undergo both genomic and epigenomic alterations, including frequent copy number changes....
Source: Clinical Epigenetics - Category: Research Authors: Julia Krushkal, Suleyman Vural, Travis L. Jensen, George Wright and Yingdong Zhao Tags: Research Source Type: research