Effectiveness of the pneumococcal polysaccharide and conjugated vaccines in elderly and high-risk populations in preventing invasive pneumococcal disease: A systematic search and review of the literature

Conclusion: The results from this review indicate a reduction of IPD in elderly and high-risk populations vaccinated with PPV23 and PCV13. The protective effect may be lower in elderly individuals >80 years and in individuals with comorbidities. However, the literature is sparse and large-scale prospective studies are needed to evaluate the effectiveness of PPV23 and PCV13 vaccination in adults in protecting against IPD.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 10.01 - Respiratory infections and bronchiectasis Source Type: research