Impaired hepatic glucose metabolism and liver- α-cell axis in mice with liver-specific ablation of the hepatocyte nuclear factor 4α (Hnf4a) gene

Hnf4a gene ablation in mouse liver causes hepatic steatosis, perturbs HDL structure and function and affects many pathways and genes related to glucose metabolism. Our aim here was to investigate the role of liver HNF4A in glucose homeostasis.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research