Maternally Expressed Gene 3 negatively regulated Decorin to Supresse Angiogenesis, Proliferation and Migration of Endothelial Cells

CONCLUSION: Our study demonstrated the anti-growth effects of MEG3 on vasculogenesis and migration of endothelial cells. Thus, by blocking the expression of Decorin in HUVECs, the overexpression of MEG3 repressed their development and might potentially alleviate the ischemic stroke.PMID:36443969 | DOI:10.2174/1566524023666221128150800

Source: Current Molecular Medicine - November 29, 2022 Category: Molecular Biology Authors: Dongwei Dai Lei Zhang Qiong Lu Jin Li Yunhai Di Chun'ou Tian Jianmin Liu Bo Hong Source Type: research