Plasma Level of Apelin as a Promising Factor for Retinopathy of Prematurity

Introduction: To investigate the relevance of plasma levels of apelin and other risk factors in infants with retinopathy of prematurity (ROP).
Methods: This was a single-center cross-sectional study. Fifty preterm infants with ROP and 50 preterm infants without ROP were enrolled. The analysis included evaluation of gestational age, birth weight, and measurement of plasma concentrations of apelin, vascular endothelial growth factor (VEGF), erythropoietin (EPO), and insulin-like growth factor (IGF-1) using enzyme-linked immunosorbent assay.
Results: The mean BW and GA of babies with ROP were considerably lower than those without ROP (P

Source: Ophthalmic Research - November 28, 2022 Category: Opthalmology Source Type: research