Nutrient-sensing mTORC1 and AMPK pathways in chronic kidney diseases

Nature Reviews Nephrology, Published online: 24 November 2022; doi:10.1038/s41581-022-00648-yThis Review discusses the mTORC1 and AMPK nutrient sensing pathways, their downstream effects in kidney cells, their roles in the development of kidney disease and the therapeutic potential of approaches that target these pathways in various chronic kidney diseases.

Source: Nature Reviews Nephrology - November 24, 2022 Category: Urology & Nephrology Authors: Christopher Huynh Jaewhee Ryu Jooho Lee Ayaka Inoki Ken Inoki Source Type: research