First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants

Conclusion
This is the largest series of CTNNA1 families that provides the first risk estimates of GC. These data will help to improve management and surveillance for these patients and support inclusion of CTNNA1 in germline testing panels.

Source: Journal of Medical Genetics - November 22, 2022 Category: Genetics & Stem Cells Authors: Coudert, M., Drouet, Y., Delhomelle, H., Svrcek, M., Benusiglio, P. R., Coulet, F., Clark, D. F., Katona, B. W., van Hest, L. P., van der Kolk, L. E., Cats, A., van Dieren, J. M., Nehoray, B., Slavin, T., Spier, I., Hüneburg, R., Lobo, S., Oliveir Tags: Cancer genetics Source Type: research