Two Feet-One Hand Syndrome: Tinea Pedis and Tinea Manuum

AbstractPurpose of ReviewWe performed a systematic review of literature from the PubMed database on January 1, 2019, to July 31, 2022. The search criteria were “(tinea manuum ORtinea pedis) AND “two feet-one hand syndrome,” with full text available and English or Spanish language required. This review will focus on the available data supporting the epidemiology, clinical manifestations, diagnosis, and treatment of the two feet-one hand syndrome.Recent FindingsTwo feet-one hand syndrome is a superficial fungal skin infection involving bilateral plantartinea pedis with coexistent unilateraltinea manuum. Toenails and fingernails may also be affected. Anthropophilic fungal species are the leading cause of dermatophytosis in adults and are isolated more often in males than in females. The species usually involved areTrichophyton rubrum,Trichophyton interdigitale, andEpidermophyton floccosum. Non-dermatophytic filamentous fungi such asHendersonula toruloidea andScytalidium hyalinum are the confirmed etiologic agents of palm, sole, and nail infections. This syndrome is highly associated with onychomycosis, and nearly 6% of the patients with onychomycosis develop two feet-one hand syndrome. Typically,tinea pedis occurs at an earlier age thantinea manuum. The infection is transmitted from one foot to the hand by excoriating the soles of the feet and picking toenails and then is transferred from the hand to the other foot. In some cases,tinea manuum develops in both hands, in con...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research