Caveolin-1 expression predicts favourable outcome and correlates with PDGFRA mutations in gastrointestinal stromal tumours (GISTs)

Conclusion
Caveolin-1 represents a novel prognostic marker in gastrointestinal stromal tumours. Further studies are warranted to validate these results and to explore the mechanisms linking Caveolin-1 expression with the PDGFRA oncogenic pathway.

Source: Journal of Clinical Pathology - November 17, 2022 Category: Pathology Authors: Bertero, L., Gambella, A., Barreca, A., Osella-Abate, S., Chiusa, L., Francia di Celle, P., Lista, P., Papotti, M., Cassoni, P. Tags: Original research Source Type: research