Basal Cell Carcinoma With Perineural Invasion: A Systematic Review and Pooled Survival Analysis

CONCLUSION Male gender, multifocal nerve involvement, presence of clinical symptoms, and PNI detected on imaging are associated with poor prognosis of BCC with PNI. The high rate of disease recurrence and suboptimal cumulative incidence of CSM highlights the importance of early clinical detection, before the onset of symptomatic PNI and multifocal nerve involvement.
Source: Dermatologic Surgery - Category: Dermatology Tags: Review Article Source Type: research