Low TLR and PSMA-TV predict biochemical response to abiraterone acetate in metastatic prostate cancer patients developing castration resistance after chemohormonal therapy at hormone-sensitive stage

CONCLUSIONS: Low PSMA-TV, low TLR were vital independent predictors of biochemical response to AA treatment and were associated with preferable prognosis in mCRPC patients. Combining ADT duration, PSMA-TV and TLR performed well in distinguishing AA responders from non-responders in mCRPC patients.PMID:36333565 | DOI:10.1007/s00432-022-04438-8

Source: Clinical Prostate Cancer - November 5, 2022 Category: Cancer & Oncology Authors: Zhi-Bin Ke Jia-Yin Chen Qi You Jiang-Bo Sun Yu-Ting Xue Xiao-Jian Ye Shao-Hao Chen Xue-Yi Xue Xiong-Lin Sun Dong-Ning Chen Yong Wei Qing-Shui Zheng Shao-Ming Chen Ning Xu Source Type: research