Update on the Management of Acanthamoeba Keratitis

AbstractPurpose or ReviewIn this article, we review the latest diagnostic modalities and management ofacanthamoeba keratitisRecent FindingsThe incidence as well as severity ofacanthamoeba keratitis is increasing, making this a challenging disease to treat, especially in patients who have a delay in diagnosis or severe disease at presentation. Newer tools such as voriconazole, miltefosine, and collagen crosslinking may be needed for infection control. Complications such as persistent infection, severe thinning, or perforation may necessitate surgical intervention.SummaryWhile traditional therapies such as polyhexamethylene biguanide and chlorhexidine remain mainstays of therapy, unresponsiveacanthamoeba keratitis may benefit from topical or oral voriconazole, oral miltefosine, or collagen crosslinking. Despite these options, management of these patients remains a challenge.
Source: Current Ophthalmology Reports - Category: Opthalmology Source Type: research