Application of a Dense SNP PCR Multiplex for High Throughput Kinship Determination using Next Generation Sequencing (NGS)

The need to identify large numbers of missing persons from mass disasters, armed conflicts and human rights abuses has become increasingly prevalent. The ForenSeq ® Kintelligence Library Prep Kit together with NGS (sometimes called massively parallel sequencing), has been designed to interrogate 10,230 SNPs for the purpose of solving cold cases, including missing persons identification. The kit allows up to 3 samples per sequencing run in order to call suffi cient SNPs for detecting relationships up to 5th degree when searching direct to consumer DNA databases, such as GEDmatch PRO™.

Source: Forensic Science International: Genetics Supplement Series - October 28, 2022 Category: Forensic Medicine Authors: Joana Antunes, Sarah Radecke, June Snedecor, Gothami Padmabandu, Kathryn M Stephens Source Type: research