Mediators of inflammation resolution and vasoactive eicosanoids in gestational diabetes and preeclampsia

Conclusion: Reduced levels of the prostacyclin metabolite 2,3-dinor-6-Keto-PGF1α may contribute to the increased risk of preeclampsia in women with GDM. The increase in 20-HETE, a vasoconstrictor and mediator of inflammation, and SPM that contribute to inflammation resolution, prior to the onset of preeclampsia require further investigation to clarify their clinical significance.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research