Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity

Alzheimer ’s Disease (AD) affects millions globally, but therapy development is lagging. New experimental systems that monitor neuronal functions in conditions approximating the AD brain may be beneficial for i...

Source: Molecular Neurodegeneration - September 21, 2022 Category: Neurology Authors: Yi-Chen Hsieh, Joseph Negri, Amy He, Richard V. Pearse II, Lei Liu, Duc M. Duong, Lori B. Chibnik, David A. Bennett, Nicholas T. Seyfried and Tracy L. Young-Pearse Tags: Research article Source Type: research