Cancers, Vol. 14, Pages 4539: A Review on Annona muricata and Its Anticancer Activity

Cancers, Vol. 14, Pages 4539: A Review on Annona muricata and Its Anticancer Activity Cancers doi: 10.3390/cancers14184539 Authors: Suganya Ilango Dipak Kumar Sahoo Biswaranjan Paital Kavibharathi Kathirvel Jerrina Issac Gabriel Kalyani Subramaniam Priyanka Jayachandran Rajendra Kumar Dash Akshaya Kumar Hati Tapas Ranjan Behera Pragnyashree Mishra Ramalingam Nirmaladevi The ongoing rise in the number of cancer cases raises concerns regarding the efficacy of the various treatment methods that are currently available. Consequently, patients are looking for alternatives to traditional cancer treatments such as surgery, chemotherapy, and radiotherapy as a replacement. Medicinal plants are universally acknowledged as the cornerstone of preventative medicine and therapeutic practices. Annona muricata is a member of the family Annonaceae and is familiar for its medicinal properties. A. muricata has been identified to have promising compounds that could potentially be utilized for the treatment of cancer. The most prevalent phytochemical components identified and isolated from this plant are alkaloids, phenols, and acetogenins. This review focuses on the role of A. muricata extract against various types of cancer, modulation of cellular proliferation and necrosis, and bioactive metabolites responsible for various pharmacological activities along with their ethnomedicinal uses. Additionally, this review highlights the molecular mechanism of the role of A....
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research