Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury

ConclusionsThe study provides an extensive resource of the cell type-specific transcriptomic responses associated with critical illness-associated AKI in humans, highlighting recurrent disease-associated signatures and inter-individual heterogeneity. Personalized molecular disease assessment in human AKI may foster the development of tailored therapies.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research