Perinatal Outcomes of Fetal Growth Restriction, Classified According to the Delphi Consensus Definition: A Prospective Observational Study

AbstractFetal Growth Restriction has been redefined on the basis of biometry (Abdominal  Circumference/Estimated Fetal Weight) beyond the original definition of failure of a fetus to reach its full growth potential irrespective of its size. The Delphi consensus has standardised the definition of early and late onset FGR using size (biometry) as well as functional parameters (dopple r blood flow). The clinical validity of this consensus in terms of perinatal outcomes has yet to be tested. The aim of the study was to assess and compare the incidence and perinatal outcomes of fetal growth restriction classified by the Delphi consensus as against conventional definitions. This wa s a prospective cohort study of 500 consecutive patients from  February 2018 onwards, in a tertiary hospital (Sir Ganga Ram Hospital, New Delhi) with a fully equipped neonatal intensive care unit. 70 patients were excluded by predefined exclusion criteria. 430 subjects were enrolled as the st udy population. Enrolled subjects, apart from a dating scan at first visit and an anomaly scan in the 2nd trimester had a transabdominal scan using a 5 MHz curvilinear probe for fetal assessment between 26 and 32 weeks with at least one scan at 31–32 weeks to identify early onset FGR. A rep eat USG between 35 and 36 weeks was conducted to identify late onset FGR. All recruited subjects were categorised as Conventional FGR i.e. AC/EFW <  10th% ile (C), early onset (C1) and late onset (C2)...
Source: Journal of Fetal Medicine - Category: Perinatology & Neonatology Source Type: research