Trem2 deletion enhances tau dispersion and pathology through microglia exosomes

Alzheimer ’s disease (AD) is a neurodegenerative disorder that manifests sequential Aβ and tau brain pathology with age-dependent onset. Variants in the microglial immune receptor TREM2 are associated with enha...

Source: Molecular Neurodegeneration - September 2, 2022 Category: Neurology Authors: Bing Zhu, Yan Liu, Spring Hwang, Kailey Archuleta, Huijie Huang, Alex Campos, Rabi Murad, Juan Pi ña-Crespo, Huaxi Xu and Timothy Y. Huang Tags: Research article Source Type: research