Viruses, Vol. 14, Pages 1899: Myotis fimbriatus Virome, a Window to Virus Diversity and Evolution in the Genus Myotis

Viruses, Vol. 14, Pages 1899: Myotis fimbriatus Virome, a Window to Virus Diversity and Evolution in the Genus Myotis Viruses doi: 10.3390/v14091899 Authors: Alix Armero Ruiya Li Kathrina Mae Bienes Xing Chen Jihao Li Shiman Xu Yanhua Chen Alice C. Hughes Nicolas Berthet Gary Wong Significant efforts have been made to characterize viral diversity in bats from China. Many of these studies were prospective and focused mainly on Rhinolophus bats that could be related to zoonotic events. However, other species of bats that are part of ecosystems identified as virus diversity hotspots have not been studied in-depth. We analyzed the virome of a group of Myotis fimbriatus bats collected from the Yunnan Province during 2020. The virome of M. fimbriatus revealed the presence of families of pathogenic viruses such as Coronavirus, Astrovirus, Mastadenovirus, and Picornavirus, among others. The viral sequences identified in M. fimbriatus were characterized by significant divergence from other known viral sequences of bat origin. Complex phylogenetic landscapes implying a tendency of co-specificity and relationships with viruses from other mammals characterize these groups. The most prevalent and abundant virus in M. fimbriatus individuals was an alphacoronavirus. The genome of this virus shows evidence of recombination and is likely the product of ancestral host-switch. The close phylogenetic and ecological relationship of some species of the Myotis genus in Chi...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research