Sotorasib Shows Intracranial Activity in Patients with < b > < i > KRAS G12C- < /i > < /b > Mutated Adenocarcinoma of the Lung and Untreated Active Brain Metastases

We present the case of a patient withKRAS G12C-mutant adenocarcinoma of the lung with active untreated brain metastases with a nearly complete intracranial response only 6 weeks after start of sotorasib illustrating the benefit of sotorasib in patients with active, previously untreated brain metastases inKRAS G12C-mutated NSCLC.Case Rep Oncol 2022;15:720 –725
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research