Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration

Conclusions
GM-CSF–induced, proreparative macrophages express arginase-1, which is required for the S3 tubular cell proliferative response that promotes renal repair after ischemia-reperfusion injury.

Source: Journal of the American Society of Nephrology : JASN - May 31, 2022 Category: Urology & Nephrology Authors: Shin, N. S., Marlier, A., Xu, L., Doilicho, N., Linberg, D., Guo, J., Cantley, L. G. Tags: Acute Kidney Injury Source Type: research