Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 Genes

CONCLUSION: These results thus indicate that Ezh2 is a key regulator of AFs' RS and this work may provide a basis for future treatments for atrial fibrosis in the elderly.PMID:35996686 | PMC:PMC9392478 | DOI:10.2147/JIR.S374951

Source: Cell Research - August 23, 2022 Category: Cytology Authors: Yingze Li Guojian Fang Wei Cao Jiali Yuan Shuai Song Hong Peng Yuepeng Wang Qunshan Wang Source Type: research