New data analysis for BioSAXS at the ESRF

This article describes FreeSAS, an open-source collection of various small-angle scattering analysis algorithms needed to reduce and analyze BioSAXS data, and Dahu, the tool used to interface data analysis with beamline control. It further presents the data-processing pipelines for the different data acquisitions modes of the beamline, using either a sample changer for individual homogeneous samples or an inline size-exclusion chromatography setup.

Source: Journal of Synchrotron Radiation - August 23, 2022 Category: Physics Authors: Kieffer, J. Brennich, M. Florial, J.-B. Oscarsson, M. De Maria Antolinos, A. Tully, M. Pernot, P. Tags: BioSAXS online data analysis solution scattering proteins biological small-angle X-ray scattering automation high brilliance structural biology high-throughput SAXS size-exclusion chromatography online purification computer programs Source Type: research