LncRNA PVT1 upregulates FBN1 by sponging miR-30b-5p to aggravate pulpitis

ConclusionPVT1 expedited the improvement of pulpitis via miR-30b-5p/FBN1.Article highlightsThe expression of PVT1 was upregulated in pulpitis.Silencing PVT1 enhanced cell proliferation and cell vitality, whereas inhibited cell inflammatory reaction in HDPFs.PVT1 expedited pulpitis via miR-30b-5p.MiR-30b-5p impeded pulpitis by targeting FBN1.
Source: Molecular and Cellular Toxicology - Category: Cytology Source Type: research