Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems

Nature Protocols, Published online: 17 August 2022; doi:10.1038/s41596-022-00733-3This protocol uses signaling networks and molecular markers recently elucidated from single-cell transcriptomic analysis of mouse foregut organogenesis to differentiate human pluripotent stem cells into digestive and respiratory organ-specific mesenchyme.

Source: Nature Protocols - August 17, 2022 Category: Biomedical Science Authors: Keishi Kishimoto Kentaro Iwasawa Alice Sorel Carlos Ferran-Heredia Lu Han Mitsuru Morimoto James M. Wells Takanori Takebe Aaron M. Zorn Source Type: research