De-labeling Penicillin Allergy in Pediatric Population

AbstractPurpose of review At present, penicillin allergy in children is misdiagnosed, leading to undesirable health consequences; thus, a correct diagnosis is needed. De-labelling penicillin allergy strategies in pediatric population is emerging in order to achieve a correct antimicrobial management.Recent findingsNew protocols, specific for pediatric population, are rising from academic societies in order to improve penicillin allergy management in children, so unnecessary tests are avoided.SummaryThis document aims to provide guidance on how to de-label penicillin allergy in children through a correct diagnosis. The workup for penicillin allergy should be based on the characteristics and severity of the index reaction, which determine the indication and risk for performing a drug provocation test and the indication or nonperformance of previous allergy tests.
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research