Changes in dimensions and functions of crystalline lens in high myopia using CASIA2 optical coherence tomography

In this study, we aim to evaluate the changes of dimensions and functions of crystalline lens in high myopia and its correlated variables using CASIA2 swept-source optical coherence tomography (SS-OCT). Methods: One hundred and thirty eligible eyes of myopic patients from 18-40 years old were enrolled and divided into low-to-moderate myopia (LMM) and high myopia (HM) groups according to spherical equivalent (SE). Anterior segment features, including lens thickness (LT), anterior radius of curvatu re (ARC), posterior radius of curvature (PRC), anterior chamber depth (ACD) and lens tilt were obtained by CASIA2. Lens power was calculated using Bennett’s formula. Sixty-seven participants were imaged at static state and accommodative state induced by −3 diopter (D) stimulus. Results: Compar ed to LMM group, HM group exhibited a significantly reduction in LT, ARC and lens tilt (all P
Source: Ophthalmic Research - Category: Opthalmology Source Type: research