The Bone Biomarker Response to an Acute Bout of Exercise: A Systematic Review with Meta-Analysis

ConclusionThe large influence of an acute bout of prolonged cycling on the bone resorption marker CTX-1, alongside the lack of a response of any biomarker to resistance or high-impact exercise types, indicate that these biomarkers may be more useful at investigating potentially osteolytic aspects of exercise, and raises questions about their suitability to investigate the osteogenic potential of different exercise types, at least in the short term and in response to a single exercise bout. Certainty in all outcomes was low or very low, due to factors including risk of bias, lack of non-exercise controls, inconsistency, imprecision and small-study effects.Protocol Registration and PublicationThis investigation was prospectively registered on the Open Science Framework Registry (https://osf.io/6f8dz) and the full protocol underwent peer review prior to conducting the investigation.
Source: Sports Medicine - Category: Sports Medicine Source Type: research