Systemic White Blood Cell Count as a Biomarker for Malignant Cerebral Edema in Large Vessel Ischemic MCA Stroke

Large middle cerebral artery (MCA) strokes remain a major cause for mortality and morbidity all over the world, and therefore early identification of patients with the highest risk for malignant cerebral edema is crucial for early intervention. Neutrophils to lymphocytes ratio (NLR) and peripheral total white blood cell (WBC) count are inflammatory markers done routinely for all patients, and this study evaluated the use of NLR and elevated white blood cell count within the first 24  h of MCA ischemic stroke onset, with the absence of significant hemorrhagic transformation, to predict malignant cerebral edema.

Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2022 Category: Neurology Authors: Faisal Ibrahim, Stephanie Menezes, Michael Buhnerkempe, Amber Fifer, Kelli Meyer, Hesham Allam Source Type: research