Within-Visit Blood Pressure Variability and All-Cause and Stroke Mortality: Thai Epidemiologic Stroke (TES) Study

This study included 19,614 participants aged 45-80 years, who were free o f stroke and had three blood pressure (BP) measurements, taken one minute apart, at baseline. Within-visit systolic blood pressure (SBP) and diastolic blood pressure (DBP) variability were expressed as the maximum absolute difference (MAD) between any two readings among the three repeated sequentia l measurements of SBP and DBP respectively. The participants were followed up for mortality. Cox regression analysis was used to identify the association of within-visit BPV with all cause and stroke mortality. Hazard ratio (HR) and 95% confidence intervals were used to illustrate the association s. Results: During a median follow-up of 11.1 years, 305 participants died of stroke, and 3,173 participants died of non-stroke cause. In unadjusted analyses, high within-visit MAD of SBP was significantly associated with all-cause (HR, 1.19; 95% CI, 1.09-1.31; p
Source: Neuroepidemiology - Category: Epidemiology Source Type: research