Plasma Cytokine Levels and Risk of HIV Type 1 (HIV-1) Transmission and Acquisition: A Nested Case-Control Study Among HIV-1-Serodiscordant Couples

Conclusions. Immune activation, as measured by levels of cytokine markers, particularly elevated levels of IL-10 and CXCL1, are associated with increased HIV-1 susceptibility and infectiousness.

Source: The Journal of Infectious Diseases - April 10, 2015 Category: Infectious Diseases Authors: Kahle, E. M., Bolton, M., Hughes, J. P., Donnell, D., Celum, C., Lingappa, J. R., Ronald, A., Cohen, C. R., de Bruyn, G., Fong, Y., Katabira, E., McElrath, M. J., Baeten, J. M., for the Partners in Prevention HSV/HIV Transmission Study Team, for the Partn Tags: HIV/AIDS Source Type: research