Monitor growth changes from central nervous system stimulants in patients with attention-deficit/hyperactivity disorder

AbstractCNS stimulants used in the management of attention-deficit/hyperactivity disorder (ADHD) may suppress appetite, and thus growth. In randomised clinical trials, CNS stimulants demonstrated growth suppression in patients, with some trials demonstrating a dose-dependent effect. Weight deficits were attenuated in adolescence, however, deficits in height were carried into adulthood. Taking CNS stimulants with or after meals, initiating treatment at an older age or using drug holidays may improve appetite and growth. The benefits achieved with these strategies must be balanced against the risks of ineffectively managed ADHD.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research