Cancers, Vol. 14, Pages 3180: Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review

Cancers, Vol. 14, Pages 3180: Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review Cancers doi: 10.3390/cancers14133180 Authors: Anne-Laure Hermann Aurore L’Herminé-Coulomb Sabine Irtan Georges Audry Liesbeth Cardoen Hervé J. Brisse Saskia Vande Perre Hubert Ducou Le Pointe Pre- and post-pubertal testicular tumors are two distinct entities in terms of epidemiology, diagnosis and treatment. Most pre-pubertal tumors are benign; the most frequent are teratomas, and the most common malignant tumors are yolk-sac tumors. Post-pubertal tumors are similar to those found in adults and are more likely to be malignant. Imaging plays a pivotal role in the diagnosis, staging and follow-up. The appearance on ultrasonography (US) is especially helpful to differentiate benign lesions that could be candidates for testis-sparing surgery from malignant ones that require radical orchidectomy. Some specific imaging patterns are described for benign lesions: epidermoid cysts, mature cystic teratomas and Leydig-cell tumors. Benign tumors tend to be well-circumscribed, with decreased Doppler flow on US, but malignancy should be suspected when US shows an inhomogeneous, not-well-described lesion with internal blood flow. Imaging features should always be interpreted in combination with clinical and biological data including serum levels of tumor markers and even intra-operative frozen sections in case of conservative surgery to raise any concerns of ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research