PPAR γ Mediates Protective Effect against Hepatic Ischemia/Reperfusion Injury via NF-κB Pathway

CONCLUSIONS: PPARγ present protective effects on HIRI by attenuating liver injury, inflammatory response, oxidative stress and apoptosis in vivo and in vitro, and its mechanism may be related to down-regulation of NF-κB signaling.PMID:35732295 | DOI:10.1080/08941939.2022.2090033

Source: Journal of Investigative Surgery - June 22, 2022 Category: Surgery Authors: Xinyu Liu Ping Zhang Xianqing Song Hengguan Cui Weixing Shen Source Type: research