Management of Henoch –Schönlein purpura

Henoch –Schönlein purpura (HSP) is the commonest childhood vasculitis, with a peak incidence in the autumn months. This supports the supposition that it is precipitated by viral infection, which then leads to the production of abnormally glycosylated immunoglobulin A (IgA) and the formation of immune co mplexes containing this IgA. All organs can be affected, but the purpuric skin lesions are necessary to make the diagnosis. There is little evidence for or against any particular therapeutic strategy and management of the acute episode is mainly supportive with analgesics as necessary.
Source: Paediatrics and Child Health - Category: Pediatrics Authors: Tags: Symposium: nephrology Source Type: research