Biphasic reward effects are characteristic of both lorcaserin and drugs of abuse: implications for treatment of substance use disorders

In conclusion, drugs of abuse and related compounds often act as biphasic modifiers of reward behavior, especially when evaluated over a broad range of doses. This property may reflect the underlying physiology of the reward system, allowing homeostatic influences on behavior.
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: Review Articles Source Type: research