Systemic Corticosteroid Uses in Endodontics- Part 2: Enhancing the Success of Local Anesthesia
Chronic inflammation in irreversible pulpitis leads to heightened sensitivity of nociceptive receptors, resulting in persistent hyperalgesia. This poses significant challenges in achieving effective anesthesia for patients with irreversible pulpitis. Various anesthetic techniques and pharmacological approaches have been employed to enhance the success of local anesthesia. Recently, the preemptive use of anti-inflammatory agents, specifically corticosteroids, has gained attention and shown promising results in randomized controlled trials. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 13, 2024 Category: Dentistry Authors: Norah Alajlan, Alonso Carrasco-Labra, Bekir Karabucak, Su-Min Lee Tags: Review Article Source Type: research

Incidence of Middle Mesial Canals in Mandibular Molars during Root Canal Treatment and Nonsurgical Retreatment
Large-scale clinical studies on the incidence of middle mesial canals (MMCs) in nonsurgical root canal treatment (RCT) and retreatment of mandibular molars are lacking. The primary aim of this observational study was to determine the incidence of MMCs in mandibular first and second  molars that received RCT or nonsurgical retreatment (NSRetx). The secondary aim was to determine factors associated with incidence of MMCs. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 7, 2024 Category: Dentistry Authors: Ali Nosrat, Prashant Verma, Omid Dianat, Noreen Ramzy, Sahar Mehrzad, Michael Valancius, Anita Aminoshariae, Ashraf F. Fouad Tags: Clinical Research Source Type: research

Incidence of Middle Mesial Canals in Mandibular Molars during Root Canal Treatment and Non-Surgical Retreatment
Large scale clinical studies on the incidence of middle mesial canals (MMCs) in non-surgical root canal treatment and retreatment of mandibular molars are lacking. The primary aim of this observational study was to determine the incidence of MMCs in mandibular first and second molars that received root canal treatment (RCT) or non-surgical retreatment (NSRetx). The secondary aim was to determine factors associated with incidence of MMCs. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 7, 2024 Category: Dentistry Authors: Ali Nosrat, Prashant Verma, Omid Dianat, Noreen Ramzy, Sahar Mehrzad, Michael Valancius, Anita Aminoshariae, Ashraf F. Fouad Tags: Clinical Research Source Type: research

Developing Advanced Patient-Specific In Silico Models: A New Era in Biomechanical Analysis of Tooth Autotransplantation
As personalized medicine advances, there is an escalating need for sophisticated tools to understand complex biomechanical phenomena in clinical research. Recognizing a significant gap, this study pioneers the development of patient-specific in silico models for tooth autotransplantation (TAT), setting a new standard for predictive accuracy and reliability in evaluating TAT outcomes. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 5, 2024 Category: Dentistry Authors: Pierre Lahoud, Reinhilde Jacobs, Seyed Ali Elahi, Maxime Ducret, Wout Lauwers, G. Harry van Lenthe, Rapha ël Richert, Mostafa EzEldeen Tags: Basic Research Source Type: research

Effects of Sodium Hypochlorite Concentration and Application Time on Bacteria in an Ex  Vivo Polymicrobial Biofilm Model
In endodontic treatment, it is important to remove or inactivate biofilms in the root canal system. We investigated the effects of different concentrations and application times of sodium hypochlorite (NaOCl) on the viability of bacteria in ex  vivo polymicrobial biofilms of different maturation levels. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 5, 2024 Category: Dentistry Authors: Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Yoko Asahi, Yusuke Takahashi, Zhejun Wang, Ya Shen, Markus Haapasalo, Mikako Hayashi Tags: Basic Research Source Type: research

Developing Advanced Patient-Specific In-Silico Models: A New Era in Biomechanical Analysis of Tooth Autotransplantation
As personalized medicine advances, there is an escalating need for sophisticated tools to understand complex biomechanical phenomena in clinical research. Recognizing a significant gap, this study pioneers the development of patient-specific in-silico models for tooth autotransplantation (TAT), setting a new standard for predictive accuracy and reliability in evaluating TAT outcomes. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 5, 2024 Category: Dentistry Authors: Pierre Lahoud, Reinhilde Jacobs, Seyed Ali Elahi, Maxime Ducret, Wout Lauwers, G. Harry van Lenthe, Rapha ël Richert, Mostafa EzEldeen Tags: Basic Research-Technology Source Type: research

Effects of sodium hypochlorite concentration and application time on bacteria in an ex vivo polymicrobial biofilm model
In endodontic treatment, it is important to remove or inactivate biofilms in the root canal system. We investigated the effects of different concentrations and application times of sodium hypochlorite (NaOCl) on the viability of bacteria in ex vivo polymicrobial biofilms of different maturation levels. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 5, 2024 Category: Dentistry Authors: Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Yoko Asahi, Yusuke Takahashi, Zhejun Wang, Ya Shen, Markus Haapasalo, Mikako Hayashi Tags: Basic Research-Biology Source Type: research

The evaluation of anti-osteoclastic activity of the novel calcium hydroxide biodegradable nanoparticles as an intracanal medicament
The aim of this study was to evaluate the anti-osteoclastic activity of calcium hydroxide-loaded poly(lactic-co-glycolic acid) nanoparticles (Ca(OH)2-loaded PLGA NPs) in comparison to calcium hydroxide nanoparticles (Ca(OH)2 NPs). (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 4, 2024 Category: Dentistry Authors: Patarawadee Promta, Patcharaporn Chaiyosang, Aussara Panya, Pongrapee Laorodphun, Warat Leelapornpisid, Napatsorn Imerb Tags: Basic Research-Technology Source Type: research

Insights into the April 2024 Issue of the Journal of Endodontics
Welcome to the latest issue of the JOE. Here, we share some of our favorite articles that are published in this issue of the Journal. We hope you look forward to reading these and other articles in the JOE. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 3, 2024 Category: Dentistry Authors: Anita Aminoshariae, Amir Azarpazhooh, Ashraf F. Fouad, Gerald N. Glickman, Jianing He, Sahng G. Kim, Anil Kishen, Ariadne M. Letra, Linda Levin, Frank C. Setzer, Franklin R. Tay, Kenneth M. Hargreaves Tags: Editorial Source Type: research

Insights into the April 2024 Issue of the JOE
Welcome to the latest issue of the JOE. Here, we share some of our favorite articles that are published in this issue of the Journal. We hope you look forward to reading these and other articles in the JOE. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 3, 2024 Category: Dentistry Authors: Anita Aminoshariae, Amir Azarpazhooh, Ashraf F. Fouad, Gerald N. Glickman, Jianing He, Sahng G. Kim, Anil Kishen, Ariadne M. Letra, Linda Levin, Frank C. Setzer, Franklin R. Tay, Kenneth M. Hargreaves Source Type: research

Retrospective follow-up assessment of risk variables influencing the outcome of autologous tooth transplantation
This retrospective study aimed to identify which patient-, donor tooth-, recipient site-, and surgical procedure-related variables may influence the outcome of tooth autotransplantation. (Source: Journal of Endodontics)
Source: Journal of Endodontics - March 2, 2024 Category: Dentistry Authors: Felipe A. Restrepo-Restrepo, Diego F. Uribe-Jaramillo, Paula A. Villa-Machado, Jos é L. Mejía-Cardona, Francesc Abella-Sans, Reyna K. Morales-Quezada, Sergio I. Tobón-Arroyave Tags: Clinical Research Source Type: research

Effect of Radiotherapy and Taper of Root Canal Preparation on the Biomechanical Behavior of Mesial Roots of Mandibular Molars
This study aimed to investigate the effect of radiotherapy and taper of root canal preparation on the biomechanical behavior of mesial roots of mandibular molars. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 29, 2024 Category: Dentistry Authors: Guilherme Pauletto, Pablo Machado Soares, Tadeu Baumhardt, Gabriel Kalil Rocha Pereira, Carlos Alexandre Souza Bier Tags: Basic Research-Technology Source Type: research

Comparative analysis of AH Plus bond strength to root canal dentin and adhesive interface quality after calcium hydroxide removal using different irrigation protocols
To evaluate the push-out bond strength (POBS) of AH Plus sealer to root dentin and the adhesive interface quality after calcium hydroxide (Ca(OH)2) intracanal dressing removal with different final irrigation protocols. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 29, 2024 Category: Dentistry Authors: Julia Menezes Savaris, Jackson Carlos Isoton, Bruna Fiorine Fluck, Maybell Tedesco, Eduardo Antunes Bortoluzzi, Lucas da Fonseca Roberti Garcia, Cleonice da Silveira Teixeira Tags: Basic Research-Technology Source Type: research

Restoration of teeth with severely compromised tooth structure using digital planning combined with orthodontic magnetic extrusion – A report of 2 cases
This report outlines two digitally planned cases in which the teeth underwent magnetic extrusion to preserve the supracrestal tissue attachment and regain the ferrule, followed by their restoration. Case 1: A 42-year-old male with the chief concern of a fractured right maxillary second premolar. Following the completion of root canal treatment, the remaining tooth structure was insufficient to create a ferrule for tooth restoration. For this scenario, a rapid magnetic extrusion technique was performed on tooth #4 to obtain an approximate 3 mm ferrule. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 28, 2024 Category: Dentistry Authors: Jaume Casaponsa, Thilla Sekar Vinothkumar, Paul M.H. Dummer, Venkateshbabu Nagendrababu, Francesc Abella Sans Tags: Case Report/Clinical Techniques Source Type: research

Evaluation of bone growth around autotransplanted teeth using cone-beam computed tomographic images
The aim of this observational study was to evaluate bone growth at the recipient site of autotransplanted teeth using cone-beam computed tomography (CBCT) images and to compare it to the control tooth. (Source: Journal of Endodontics)
Source: Journal of Endodontics - February 28, 2024 Category: Dentistry Authors: Ludimila Saiter Assis Beltrame, Juliana Delatorre Bronzato, Tereza Jacy da Silva Almeida, Jo ão Batista Gagno Intra, Fernanda Carneiro Nunes, Cleber de Freitas Britto, Natalia Barcellos de Freitas Coutinho, Glauco Rangel Zanetti, Marcos Frozoni Tags: Clinical Research Source Type: research