Cardiac Malformations Not Up With First-Trimester Ondansetron
WEDNESDAY, Dec. 19, 2018 -- First-trimester ondansetron use is associated with a small increased risk for oral cleft but no increased risk for congenital malformations or cardiac malformations, according to a study published in the Dec. 18 issue of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 19, 2018 Category: Pharmaceuticals Source Type: news

Ondansetron in Early Pregnancy Doesn't Promote Cardiac Defects Ondansetron in Early Pregnancy Doesn't Promote Cardiac Defects
The antiemetic ondansetron does not meaningfully increase the risk for congenital malformations overall when taken for nausea and vomiting early in pregnancy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 18, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Morning sickness pill study finds small link to increased risk of clefts but 'not a cause for alarm'
A new study finds no association between ondansetron and an increased risk of heart-related malformations or other malformations in newborns overall. It found a small increased risk of oral clefts, including cleft lip and cleft palate, in babies born to women who used ondansetron. (Source: CNN.com - Health)
Source: CNN.com - Health - December 18, 2018 Category: Consumer Health News Source Type: news

Prevention of Post Spinal Shivering Prevention of Post Spinal Shivering
This study evaluated the efficacy of dexmedetomidine and ondansetron to reduce the incidence and severity of shivering after intrathecal blocks.BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 18, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Ondansetron Hydrochloride Injection (Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 18, 2018 Category: Drugs & Pharmacology Source Type: news

Ondansetron Hydrochloride Injection (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 11, 2018 Category: Drugs & Pharmacology Source Type: news

Ondansetron Dosing in C-Section Under Spinal Anesthesia Ondansetron Dosing in C-Section Under Spinal Anesthesia
What is the minimal weight-based dose of ondansetron required to reduce hypotension after spinal anesthesia in women undergoing cesarean section?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 26, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

More Data Indicate Ondansetron Is Safe for Morning Sickness More Data Indicate Ondansetron Is Safe for Morning Sickness
A large data set composed of two birth defect studies confirms there is little risk for teratogenicity when off-label ondansetron is taken for nausea and vomiting during the first trimester of pregnancy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 20, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Ondansetron Hydrochloride Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 18, 2018 Category: Drugs & Pharmacology Source Type: news

Ondansetron Hydrochloride Injection (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 17, 2018 Category: Drugs & Pharmacology Source Type: news

Zuplenz (Ondansetron Oral Soluble Film) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 26, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Drug Safety Communication: New information regarding QT prolongation with ondansetron (Zofran)
The U.S. Food and Drug Administration (FDA) is informing healthcare professionals and the public that preliminary results from a recently completed clinical study suggest that a 32 mg single intravenous dose of ondansetron (Zofran, ondansetron hydrochloride, and generics) may affect the electrical activity of the heart (QT interval prolongation), which could pre-dispose patients to develop an abnormal and potentially fatal heart rhythm known as Torsades de Pointes. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 11, 2017 Category: Drugs & Pharmacology Source Type: news

Case series: treating cannabinoid hyperemesis syndrome with capsaicin cream
3 out of 5 stars Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Dezieck L et al. Clin Toxicol 2017 Sep;55:908-913. Abstract  Cannabis hyperemesis syndrome (CHS) is a form of cyclic vomiting characterized by: chronic marijuana use recurrent vomiting, and lack of alternate explanation for symptoms A striking feature is that although CHS-induced nausea and vomiting are frequently resistant to standard antiemetics such as ondansetron, patients often report that very hot showers or baths relieve their symptoms. Several years ago, Jeff Lapoint noticed that the...
Source: The Poison Review - December 5, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical cannabinoid hyperemesis syndrome capsaicin treatment TRPV1 receptor Source Type: news

Fresenius Kabi Issues Voluntary Nationwide Recall of Midazolam Injection, USP, 2 mg/2 mL Due to Reports of Blister Packages Containing Syringes of Ondansetron Injection, USP, 4 mg/2 mL
Fresenius Kabi USA is voluntarily recalling Lot 6400048 of Midazolam Injection, USP, 2 mg/2 mL packaged in a 2 mL prefilled single-use glass syringe to the hospital/user level. The product mislabeled as Midazolam Injection, USP, 2 mg/2 mL contains syringes containing and labeled as Ondansetron Injection, USP, 4 mg/2 mL. (Source: Food and Drug Administration)
Source: Food and Drug Administration - November 3, 2017 Category: Food Science Source Type: news