anal cancer poor chemo candidate
I have an elderly patient with a T3N0 anal squam.
Not a great 5FU/MMC candidate per med onc.
If you were to try to twist the arm of med onc into something radiosensitizing, what would you consider? xeloda or weekly cis?
I see this case series using just 5FU.
Any thoughts are appreciated.
Effective treatment of anal cancer in the elderly with low-dose chemoradiotherapy - British Journal of Cancer (Source: Student Doctor Network)
Source: Student Doctor Network - August 15, 2023 Category: Universities & Medical Training Authors: BobbyHeenan Tags: Radiation Oncology Source Type: forums
Logic behind different concurrent chemotherapy regimens
Hello everyone,
As I'm studying for boards (on GI cancers now), I have been noticing the plethora of concurrent chemotherapy regimens that have been tried over the years and I'm trying to make sense of this information.
As general rules of thumb, do we expect certain concurrent chemotherapy regimens to work better in adenocarcinoma compared to SCC or vice versa? (5FU/cisplatin/carboplatin/etoposide/xeloda/epirubicin/leucovorin)
For example, why would you treat both SCC and...
Read more (Source: Student Doctor Network)
Source: Student Doctor Network - March 8, 2021 Category: Universities & Medical Training Authors: TurboTesla Tags: Radiation Oncology Source Type: forums
Triple Neg with residual post neoadjuvant....
.... med onc wants to give Xeloda during radiation. Are you hypofractionating or standard fractionation? (Source: Student Doctor Network)
Source: Student Doctor Network - January 28, 2021 Category: Universities & Medical Training Authors: Mandelin Rain Tags: Radiation Oncology Source Type: forums
Colorectal ADK in 95 yo patient
Dear colleagues,
I have a 95 yo female patient, very well conserved, ambulant . No severe comorbidities.
She presented for low rectum ademocarcinoma invading partially the internal anal sphincter with no fecal incontinence.
She complains of post defecation pain and rectorrhagia.
Pelvic MRI showed no LNs.
She is not operable.
She will receive xeloda with concomitant radiation.
What would you propose as for dose and fractionation?
-45/25 with boost to small pelvis and tumor
- 25 in 5...
Colorectal ADK in 95 yo patient (Source: Student Doctor Network)
Source: Student Doctor Network - June 6, 2017 Category: Universities & Medical Training Authors: Kroll2013 Source Type: forums
Re: Loss of fingerprints secondary to palmoplantar erythrodysesthesia in a patient on capecitabine chemotherapy
(Source: BMJ Comments)
Source: BMJ Comments - November 30, 2015 Category: Journals (General) Source Type: forums
