HEAL Workshop: Target Validation for Non-Addictive Therapeutics Development for Pain (DAY 2)
Despite advances in the understanding of pain physiology there has been a paucity of novel analgesic medications developed to address the still high unmet need of pain patients especially those who rely on addictive opioid medicines for pain relief. The successful development of novel non-opioid, non-addictive therapeutics requires advances in preclinical target validation that demonstrate sufficient human disease relevance to trigger investment in non-clinical development and subsequent clinical trials to obtain proof of biology and early proof of efficacy before registrational studies. Translating novel target discoverie...
Source: Videocast - All Events - October 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
HEAL Workshop: Target Validation for Non-Addictive Therapeutics Development for Pain (DAY 1)
Despite advances in the understanding of pain physiology there has been a paucity of novel analgesic medications developed to address the still high unmet need of pain patients especially those who rely on addictive opioid medicines for pain relief. The successful development of novel non-opioid, non-addictive therapeutics requires advances in preclinical target validation that demonstrate sufficient human disease relevance to trigger investment in non-clinical development and subsequent clinical trials to obtain proof of biology and early proof of efficacy before registrational studies. Translating novel target discoverie...
Source: Videocast - All Events - October 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Virtual Workshop Metabolism-based Therapies for Epilepsy Workshop
Metabolism-based therapies for epilepsy have been suggested since antiquity but the modern use of ketogenic diets for epilepsy treatment has been in medical practice for nearly 100 years. The use of these diets has since expanded to less intensive regimens and supplements. Despite decades of research, the mechanisms underlying the efficacy of these treatments is not completely understood, although important factors have been identified.
The nature of these treatments (e.g., altered diet regimens) has made rigorous studies a challenge, both in the preclinical and clinical spaces. Bench-bedside translation has been a challen...
Source: Videocast - All Events - September 29, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Novel and Exceptional Technology and Research Advisory Committee (NExTRAC) 2020 Fall Meeting (Day 1)
On November 9-10, 2020, NIH will be hosting a virtual meeting of the Novel and Exceptional Technology and Research Advisory Committee (NExTRAC). The NExTRAC provides recommendations to the NIH Director and serves as a public forum for the discussion of the scientific, safety, and ethical issues associated with emerging biotechnologies.
The meeting will include (1) a workshop to examine existing biosafety guidance for contained gene drive research and to discuss potential conditions under which NIH could consider supporting field release of gene drive- modified organisms and (2) discussion of a draft report conceptualizing ...
Source: Videocast - All Events - September 23, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Novel and Exceptional Technology and Research Advisory Committee (NExTRAC) 2020 Fall Meeting (Day 2)
On November 9-10, 2020, NIH will be hosting a virtual meeting of the Novel and Exceptional Technology and Research Advisory Committee (NExTRAC). The NExTRAC provides recommendations to the NIH Director and serves as a public forum for the discussion of the scientific, safety, and ethical issues associated with emerging biotechnologies. The meeting will include (1) a workshop to examine existing biosafety guidance for contained gene drive research and to discuss potential conditions under which NIH could consider supporting field release of gene drive- modified organisms and (2) discussion of a draft report conceptualizing ...
Source: Videocast - All Events - September 23, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NCCIH Workshop 2020: Exploring the Mechanisms Underlying Analgesic Properties of Minor Cannabinoids and Terpenes
The overall goals of this workshop are two fold — one is to convene principal investigators funded by NCCIH on the topic of the analgesic properties of minor cannabinoids and terpenes from natural products and the underlying mechanisms; and the other is to discuss current research barriers and opportunities on this topic. This workshop is aligned with NCCIH ’ s mission to support research on the fundamental science, safety, and usefulness of complementary and integrative health approaches. Specifically, minor cannabinoids and terpenes from natural products are part of complementary interventions supported by NCCIH. The...
Source: Videocast - All Events - September 23, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Novel and Exceptional Technology and Research Advisory Committee (NExTRAC) 2020 Fall Meeting
On November 9-10, 2020, NIH will be hosting a virtual meeting of the Novel and Exceptional Technology and Research Advisory Committee (NExTRAC). The NExTRAC provides recommendations to the NIH Director and serves as a public forum for the discussion of the scientific, safety, and ethical issues associated with emerging biotechnologies.
The meeting will include (1) a workshop to examine existing biosafety guidance for contained gene drive research and to discuss potential conditions under which NIH could consider supporting field release of gene drive- modified organisms and (2) discussion of a draft report conceptualizing ...
Source: Videocast - All Events - September 18, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Developing Meaningful Endpoints for Pain Clinical Trials (Day 2)
More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance on the prescription of opioids for chronic pain, contributing to a significant and alarming epidemic of opioid overdose deaths and addiction. Innovative scientific solutions to develop non-opioid, non-addictive alternative treatment options are thus urgently needed.
One of the goals of the Helping to End Addiction Long-term (HEAL) Initiative is to accelerate the discovery and preclinical development of new medications and devices t...
Source: Videocast - All Events - September 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Developing Meaningful Endpoints for Pain Clinical Trials (Day 1)
More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance on the prescription of opioids for chronic pain, contributing to a significant and alarming epidemic of opioid overdose deaths and addiction. Innovative scientific solutions to develop non-opioid, non-addictive alternative treatment options are thus urgently needed.
One of the goals of the Helping to End Addiction Long-term (HEAL) Initiative is to accelerate the discovery and preclinical development of new medications and devices t...
Source: Videocast - All Events - September 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Navigating Pediatric to Adult Health Care: Lost in Transition Workshop (Day 2)
With improved rates of survival in childhood illnesses in the United States and globally, individuals are living longer with one or more chronic conditions. To meet the needs of diverse populations with chronic physical/medical conditions or intellectual/developmental disabilities as they transition from pediatric to adult centric services, barriers to successful health care transition (HCT), methods and measures for defining HCT, and the identification of promising practices must be better understood. In accordance with leading efforts in the transition field, the health care transition needs to take occur within a contex...
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Navigating Pediatric to Adult Health Care: Lost in Transition Workshop (Day 1)
With improved rates of survival in childhood illnesses in the United States and globally, individuals are living longer with one or more chronic conditions. To meet the needs of diverse populations with chronic physical/medical conditions or intellectual/developmental disabilities as they transition from pediatric to adult centric services, barriers to successful health care transition (HCT), methods and measures for defining HCT, and the identification of promising practices must be better understood. In accordance with leading efforts in the transition field, the health care transition needs to take occur within a contex...
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NIMHD The Role of Work in Health Disparities in the U.S. Workshop (Day 2)
Work is a social determinant of health that may explain a considerable amount of health disparities for racial and ethnic minority and socioeconomically disadvantaged populations. This workshop will convene experts from the research fields of health disparities, population sciences, labor economics, occupational health, epidemiology, and organizational sociology and psychology to consider work as a social determinant of health and identify potential mechanisms and interventions to address health disparities.Air date: 9/29/2020 10:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NIMHD The Role of Work in Health Disparities in the U.S. Workshop (Day 1)
Work is a social determinant of health that may explain a considerable amount of health disparities for racial and ethnic minority and socioeconomically disadvantaged populations. This workshop will convene experts from the research fields of health disparities, population sciences, labor economics, occupational health, epidemiology, and organizational sociology and psychology to consider work as a social determinant of health and identify potential mechanisms and interventions to address health disparities.Air date: 9/28/2020 10:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy (Day 1)
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) and the Center for Biologics Evaluation and Research (CBER) at the U.S. Food and Drug Administration (FDA) are co-hosting a virtual Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy. This meeting will bring together scientists, therapeutic developers and patient representatives to focus on immunogenicity issues related to the systemic administration of AAV gene therapy products and identify solutions for those issues.For more information go tohttps://events-supp...
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy (Day 2)
This meeting will bring together scientists, therapeutic developers and patient representatives to focus on immunogenicity issues related to the systemic administration of AAV gene therapy products and identify solutions for those issues.For more information go tohttps://events-support.com/events/NCATS_Gene_Therapies_November_2020Air date: 12/1/2020 9:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
