Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract
Conditions: Endoscopic Vacuum Therapy; Anastomotic Leak; Esophageal Perforation; Esophageal Perforation, Traumatic; EsoSponge; VACStent Intervention: Other: Observational Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 7, 2022 Category: Research Source Type: clinical trials
Traditional Chinese medicine based on Tongjiang methodology combined with proton pump inhibitor (PPI) step-down in treating non-erosive reflux disease: a study protocol for a multicentered, randomized controlled clinical trial
DiscussionPrevious research has shown that TCM is capable to alleviate NERD symptoms. This trial will help to provide a better understanding of the synergistic efficiency of the combination of TCM and PPIs, to explore whether the dosage of PPIs can be reduced after the supplement of TCM granules and to provide a feasible plan to reduce dependencies or withdraw NERD patients from PPIs. The outcome of this trial is expected to reduce the symptom recurrence rates, lessen patients ’ physical and psychological burdens, and achieve good social benefits.Trial registrationClinicaltrials.gov NCT04340297. Registered on April 9, 2020 (Source: Trials)
Source: Trials - October 18, 2022 Category: Research Source Type: clinical trials
Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial
DiscussionPropofol-based deep sedation without intubation is widely used in painless GI endoscopy. However, adverse events such as hypoxemia often occur clinically. We expect to assess the effect of lidocaine on reducing the incidence of oxygen-desaturation episodes, cardiovascular events, and involuntary body movement. We believe that the results of this trial will provide an effective and safe method for painless GI endoscopy.Trial registrationChinese Clinical Trial Registry ChiCTR2100053818. Registered on 30 November 2021. (Source: Trials)
Source: Trials - September 24, 2022 Category: Research Source Type: clinical trials
