Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: European Review for Medical and Pharmacological Sciences - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: Pharmacological Reviews - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: European Review for Medical and Pharmacological Sciences - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: Pharmacological Reviews - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: European Review for Medical and Pharmacological Sciences - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: Pharmacological Reviews - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: European Review for Medical and Pharmacological Sciences - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: Pharmacological Reviews - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease
CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve advers...
Source: European Review for Medical and Pharmacological Sciences - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research

Therapeutic Efficacy of Platelet Transfusion And Analysis of Influencing Factors in 364 Patients
CONCLUSION: To reduce PTR, multiple factors should be considered comprehensively when PLT transfusion therapy is to be implemented in clinical practice. PLT antibody is the main immune factor causing PTR.PMID:36758527 | DOI:10.1159/000529542 (Source: Acta Haematologica)
Source: Acta Haematologica - February 9, 2023 Category: Hematology Authors: Xiaoye Sun Yifeng Cai Hui Ni Hui Cong Source Type: research

Therapeutic Efficacy of Platelet Transfusion And Analysis of Influencing Factors in 364 Patients
CONCLUSION: To reduce PTR, multiple factors should be considered comprehensively when PLT transfusion therapy is to be implemented in clinical practice. PLT antibody is the main immune factor causing PTR.PMID:36758527 | DOI:10.1159/000529542 (Source: Acta Haematologica)
Source: Acta Haematologica - February 9, 2023 Category: Hematology Authors: Xiaoye Sun Yifeng Cai Hui Ni Hui Cong Source Type: research