Modeling Tic Change During Behavior Therapy for Tics
Conditions: Chronic Tic Disorder Interventions: Behavioral: CBIT Sponsors: University of Minnesota Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials

Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
Conditions: Tourette Syndrome; Persistent Tic Disorder Interventions: Other: CBIT Sponsors: University of Minnesota Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials

The CBIT  + TMS trial: study protocol for a two-phase randomized controlled trial testing neuromodulation to augment behavior therapy for youth with chronic tics
DiscussionThis clinical trial is one of few to date testing TMS augmentation of therapy in a pediatric sample. The results will provide insight into whether TMS is a potentially viable strategy for enhancing CBIT efficacy and reveal potential neural and behavioral mechanisms of change.Trial registrationClinicalTrials.govNCT04578912. Registered on October 8, 2020. (Source: Trials)
Source: Trials - July 3, 2023 Category: Research Source Type: clinical trials

Efficiency of probiotics in elderly patients undergoing orthopedic surgery for postoperative cognitive dysfunction: a study protocol for a multicenter, randomized controlled trial
This study aims to intervene with the intestinal flora imbalance using probiotics during the perioperative period to reduce the incidence of POCD in elderly patients after orthopedic surgery and to provide new ideas and methods for the clinical prevention and treatment of POCD.MethodsA multicenter, double-blind, placebo-controlled clinical trial will be performed to evaluate the efficacy of probiotics in elderly patients undergoing orthopedic surgery. Participants (n = 220) will receive probiotics (Peifeikang, Live Combined Bifidobacterium, 210 mg per capsule, twice a day, four capsules each time, which contains Bifid...
Source: Trials - February 25, 2023 Category: Research Source Type: clinical trials

Tourette Discrimination (TD) Stigma Scale
Conditions:   Tourette Syndrome;   Tourette Syndrome in Children;   Tourette Syndrome in Adolescence;   Tic Disorder, Childhood;   Tics Intervention:   Sponsors:   Wake Forest University Health Sciences;   Tourette Association of America;   University of Rochester Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2023 Category: Research Source Type: clinical trials

Efficacy and safety of Jiu-Wei-Xi-Feng granules for treating tic disorders in children: study protocol for a randomized controlled equivalence trial
This study is designed to evaluate the clinical equivalence between Jiu-Wei-Xi-Feng granules (Os Draconis replaced byConcha Ostreae) (JWXFD) and Jiu-Wei-Xi-Feng granules (original formula) (JWXFO) in children with TD (consumption of renal yin and liver wind stirring up internally syndrome).Methods/designThis is a multicenter, randomized, double-blind, equivalence trial comparing the efficacy and safety of JWXFD and JWXFO in treating Children with tic disorders (consumption of renal yin and liver wind stirring up internally syndrome). A total of 288 patients will be recruited and randomly assigned to two groups in a 1:1 rat...
Source: Trials - October 22, 2022 Category: Research Source Type: clinical trials

The Findings of Magnetic Resonance Imaging in Subtypes of Tics-related Disorders
Condition:   Tourette Syndrome in Children Intervention:   Diagnostic Test: Brain MRI Sponsor:   National Taiwan University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2022 Category: Research Source Type: clinical trials