Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs
Conditions: Immunosuppression Interventions: Drug: Tacrolimus Pill; Drug: Tacrolimus capsule Sponsors: Edward Geissler; Chiesi Pharmaceuticals GmbH Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 20, 2024 Category: Research Source Type: clinical trials
Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant
Conditions: Acute Leukemia; Myelodysplastic Syndrome; Myeloproliferative Disorders Interventions: Drug: ATG dosing platform when combined with standard tacrolimus and mini methotrexate Sponsors: University of Alabama at Birmingham Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 19, 2024 Category: Research Source Type: clinical trials
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Adults With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor
Conditions: Dermatitis Atopic Interventions: Drug: Amlitelimab; Drug: Placebo; Drug: Topical corticosteroids; Drug: Topical tacrolimus or pimecrolimus Sponsors: Sanofi Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2024 Category: Research Source Type: clinical trials
Phase 3 Study of Tacrolimus Minimization in Kidney Transplant Recipients Selected According to the AGORA Algorithm for Their Low Immunological Risk and Medium-term Graft Failure
Conditions: Organ Grafts Interventions: Drug: TACROLIMUS Sponsors: Nantes University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
Evaluating LP-10 in Subjects With OLP
Conditions: Oral Lichen Planus Interventions: Drug: LP-10 (Liposomal Tacrolimus) Sponsors: Lipella Pharmaceuticals, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials
Tacrolimus versus mycophenolate for AutoImmune hepatitis patients with incompLete response On first-line therapy (TAILOR study): a study protocol for a phase III, open-label, multicentre, randomised controlled trial
DiscussionThis is the first randomised controlled trial comparing two second-line therapies for AIH. Currently, second-line treatment is based on retrospective cohort studies. The rarity of AIH is the main issue in clinical research for alternative treatment options. The results of this trial can be implemented in existing international clinical guidelines.Trial registrationClinicalTrials.govNCT05221411. Retrospectively registered on 3 February 2022; EudraCT number 2021 –003420-33. Prospectively registered on 16 June 2021. (Source: Trials)
Source: Trials - January 17, 2024 Category: Research Source Type: clinical trials
Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome
Conditions: Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome Interventions: Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Dual-Energy Computed Tomography; Procedure: Echocardiography; Drug: Fludarabine; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Procedure: Multigated Acquisition Scan; Biological: Partially Engineered T-regulatory Cell Donor Graft TRGFT-201; Drug: Tacrolimus; Drug: Thiotepa; Radiation: Total Marrow and Lymphoid Irradiation Sponsors: City of Hope Medical Center; National Cancer Institute (NCI) Recruit...
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials
Prospective, Multicenter Clinical Study of Prolonged-release Tacrolimus in Stable Pediatric Liver Transplant Recipients
Conditions: Liver Transplant Interventions: Drug: Tacrolimus Sustained-release Capsules Sponsors: RenJi Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials
Efficacy and Safety of Immunosuppressive Withdrawal After Pediatric Liver Transplantation
Conditions: Immune Tolerance; Immunosuppression; Liver Transplant; Complications Interventions: Drug: Tacrolimus or Cyclosporine A Sponsors: Wei Gao Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials
Early Conversion of Prolonged-release Tacrolimus in Liver Transplantation.
Conditions: Liver Transplantation Interventions: Drug: Tacrolimus Sustained-release Capsules Sponsors: Beijing Tsinghua Chang Gung Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials
Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Conditions: Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome Interventions: Procedure: Biospecimen Collection; Procedure: Chest Computed Tomography; Procedure: Echocardiography; Procedure: Hematopoietic Cell Transplantation; Drug: Methotrexate; Procedure: Multigated Acquisition Scan; Drug: Ruxolitinib Phosphate; Drug: Tacrolimus Sponsors: City of Hope Medical Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients
Conditions: Kidney Transplant Rejection Interventions: Drug: AT-1501; Drug: Tacrolimus Sponsors: Eledon Pharmaceuticals Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 10, 2023 Category: Research Source Type: clinical trials
Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment
Conditions: Pharmacokinetics; Area Under Curve; Tacrolimus; Immunosuppressive Agents; Mycophenolic Acid Interventions: Other: venipuncture Sponsors: Radboud University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials
Use of Belatacept to Delay Tacrolimus Initiation in Kidney Transplant Patients With Delayed Graft Function
Conditions: Belatacept Impact on Patients With GDF Interventions: Behavioral: impact of administering one dose of belatacept on eGFR Sponsors: Methodist Health System Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 20, 2023 Category: Research Source Type: clinical trials
Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)
Conditions: Secondary Malignant Neoplasm of Retroperitoneum; Secondary Malignant Neoplasm of Peritoneum; Pseudomyxoma Peritonei Interventions: Procedure: Intestinal, Multivisceral or Modified Multivisceral Transplantation; Drug: Alemtuzumab; Drug: Tacrolimus; Drug: Sirolimus Sponsors: Case Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials
