Doxycycline post-exposure prophylaxis for prevention of sexually transmitted infections among Kenyan women using HIV pre-exposure prophylaxis: study protocol for an open-label randomized trial
DiscussionThe results of this trial may have immediate implications for the global epidemic of STIs and sexual health. If effective, dPEP could put STI prevention into women ’s hands. While dPEP may be able to prevent STIs, it carries important risks that could counter its benefits; global debate about the balance of these potential risks and benefits requires data to inform policy and implementation and our study aims to fill this gap.Trial registrationClinicalTrials.govNCT04050540. (Source: Trials)
Source: Trials - June 16, 2022 Category: Research Source Type: clinical trials

Health Information and Monitoring of Sexually Transmitted Infections (SIM study): a single-center, parallel, three-arm randomized controlled trial protocol for enhancing adherence to syphilis treatment and follow-up
ConclusionIf we find differences in effectiveness, a major change in the conventional approach for this patient population may be needed, potentially affecting current Brazilian health policy strategies.Trial registrationNTC04753125. Version 1 of protocol 1/09/2020. (Source: Trials)
Source: Trials - May 26, 2022 Category: Research Source Type: clinical trials

Vienna HIV Infection Via Sex Study
Conditions:   HIV Infections;   HIV Pre-Exposure Prophylaxis;   Sexually Transmitted Diseases;   Gonorrhea;   Chlamydia;   Syphilis Intervention:   Sponsor:   Medical University of Vienna Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 13, 2022 Category: Research Source Type: clinical trials