MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma
Conditions: Leiomyosarcoma; Liposarcoma; Synovial Sarcoma; Angiosarcoma; Undifferentiated Pleomorphic Sarcoma; Epithelioid Sarcoma; Malignant Peripheral Nerve Sheath Tumors; Fibrosarcoma; Pleomorphic Rhabdomyosarcoma; Endometrial Stromal Sarcoma; Desmoplastic Small Round Cell Tumor Interventions: Biological: MASCT-I; Drug: Doxorubicin; Drug: Ifosfamide Sponsors: HRYZ Biotech Co. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)
Conditions: Ewing Sarcoma; Rhabdomyosarcoma; Synovial Sarcoma Interventions: Biological: Peptide vaccine IPX Sponsors: University Hospital Tuebingen; Deutsches Konsortium f ürTranslationale Krebsforschung (DKTK); Cooperative Ewing Sarkom Studiengruppe; Cooperative Weichteilsarkom Study Group Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials
Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1
Conditions: Synovial Sarcoma Interventions: Drug: Fludarabine phosphate; Drug: NY-ESO-1 TCR/IL-15 NK; Drug: Cyclophosphamide Sponsors: M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials
Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer
Condition: Neoplasms Interventions: Drug: GSK3901961; Drug: Cyclophosphamide; Drug: Fludarabine Sponsor: GlaxoSmithKline Terminated (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials
Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer
Conditions: Neoplasms Interventions: Drug: GSK3901961; Drug: Cyclophosphamide; Drug: Fludarabine Sponsors: GlaxoSmithKline Terminated (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials
Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Condition: Neoplasms Intervention: Drug: Letetresgene autoleucel Sponsor: GlaxoSmithKline Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 15, 2023 Category: Research Source Type: clinical trials
