False-positive human immunodeficiency virus nuclear acid amplification technique testing following therapy with transgenic T cell receptor cellular therapy for synovial sarcoma
Bone Marrow Transplantation, Published online: 17 May 2024; doi:10.1038/s41409-024-02307-1False-positive human immunodeficiency virus nuclear acid amplification technique testing following therapy with transgenic T cell receptor cellular therapy for synovial sarcoma (Source: Bone Marrow Transplantation)
Source: Bone Marrow Transplantation - May 17, 2024 Category: Hematology Authors: Michael Slade Dejka Araujo Min Du Bijal Parikh Neil Anderson Brian A. Van Tine Armin Ghobadi Source Type: research

Development of a nomogram for predicting cancer-specific survival in synovial sarcoma: Insights from SEER and a Chinese cohort study
Asian J Surg. 2024 May 8:S1015-9584(24)00910-2. doi: 10.1016/j.asjsur.2024.05.022. Online ahead of print.NO ABSTRACTPMID:38724380 | DOI:10.1016/j.asjsur.2024.05.022 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - May 9, 2024 Category: Surgery Authors: Jin Yuan Shengji Yu Source Type: research

Development of a nomogram for predicting cancer-specific survival in synovial sarcoma: Insights from SEER and a Chinese cohort study
Asian J Surg. 2024 May 8:S1015-9584(24)00910-2. doi: 10.1016/j.asjsur.2024.05.022. Online ahead of print.NO ABSTRACTPMID:38724380 | DOI:10.1016/j.asjsur.2024.05.022 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - May 9, 2024 Category: Surgery Authors: Jin Yuan Shengji Yu Source Type: research

Sarcoma of the Lung and Mediastinum
Surg Pathol Clin. 2024 Jun;17(2):243-255. doi: 10.1016/j.path.2023.11.008. Epub 2023 Dec 15.ABSTRACTPrimary sarcoma of the lung and mediastinum is rare. The diagnosis requires careful exclusion of sarcomatoid carcinoma, sarcomatoid mesothelioma, and metastases from extra-thoracic sites. This review summarizes the key morphologic, immunohistochemical, and molecular characteristics of sarcomas that are encountered in the lung and mediastinum. The tumor types discussed are synovial sarcoma, well-differentiated/dedifferentiated liposarcoma, myxoid pleomorphic liposarcoma, intimal sarcoma of the pulmonary artery, inflammatory m...
Source: Clinical Lung Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Ken-Ichi Yoshida Akihiko Yoshida Source Type: research

Primary pulmonary monophasic synovial sarcoma initially presenting with bloody pleural effusion: A case report and literature review
We report the first case of a 57-year -old man with bloody pleural effusion as an initial manifestation of PPSS in the middle lobe of the right lung diagnosed after surgery. Diagnosis: Chest computed tomography (CT) revealed a mass in the middle lobe of the right lung, which was pathologically diagnosed as a monophasic SS after surgical resection. Interventions: Ten days after preoperative closed chest drainage, a right thoracotomy was performed to remove the right middle lobe of the lung. Outcomes: The patient recovered smoothly and was discharged from the hospital without any other postoperative treatment. A follow-up ch...
Source: Clinical Case Reports - April 27, 2024 Category: General Medicine Authors: Tengcheng Yin, Bing Liu, Jinru Xue, Xiyu Liu, Shengtao Shang, Yan Wang Tags: CASE REPORT Source Type: research

Tumours of the foot: A 10 years retrospective analysis
CONCLUSION: Foot tumours are relatively rare, mostly originating from soft tissue and exhibiting a benign nature. Nonetheless, a noteworthy proportion-approximately a quarter of these tumours-demonstrate malignancy. The surgical interventions undertaken in managing these tumours and associated functional outcomes generally yield acceptable results.PMID:38662594 | DOI:10.1177/10225536241248706 (Source: Journal of Orthopaedic Surgery)
Source: Journal of Orthopaedic Surgery - April 25, 2024 Category: Orthopaedics Authors: Vivek Ajit Singh Vinesh Sandhu Choo Tze Yong Nor Faissal Yasin Source Type: research

Tumours of the foot: A 10 years retrospective analysis
CONCLUSION: Foot tumours are relatively rare, mostly originating from soft tissue and exhibiting a benign nature. Nonetheless, a noteworthy proportion-approximately a quarter of these tumours-demonstrate malignancy. The surgical interventions undertaken in managing these tumours and associated functional outcomes generally yield acceptable results.PMID:38662594 | DOI:10.1177/10225536241248706 (Source: Journal of Orthopaedic Surgery)
Source: Journal of Orthopaedic Surgery - April 25, 2024 Category: Orthopaedics Authors: Vivek Ajit Singh Vinesh Sandhu Choo Tze Yong Nor Faissal Yasin Source Type: research

Tumours of the foot: A 10 years retrospective analysis
CONCLUSION: Foot tumours are relatively rare, mostly originating from soft tissue and exhibiting a benign nature. Nonetheless, a noteworthy proportion-approximately a quarter of these tumours-demonstrate malignancy. The surgical interventions undertaken in managing these tumours and associated functional outcomes generally yield acceptable results.PMID:38662594 | DOI:10.1177/10225536241248706 (Source: Journal of Orthopaedic Surgery)
Source: Journal of Orthopaedic Surgery - April 25, 2024 Category: Orthopaedics Authors: Vivek Ajit Singh Vinesh Sandhu Choo Tze Yong Nor Faissal Yasin Source Type: research

Complete resection of a giant intrapericardial cardiac synovial sarcoma
Synovial sarcoma of the heart is a rare tumor. Herein we would like to report a case of giant intrapericardial cardiac synovial sarcoma that originated from the right ventricle and grew outward near the diaphr... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 18, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Binyue Wang and Ligang Liu Tags: Case Report Source Type: research

Extensive surgical resections for rare pleural neoplasms: a single-center experience with a yolk sac tumor and synovial sarcoma
Pleural neoplasms are rare and can be subdivided into pleural metastasis and primary pleural neoplasms. Non-mesothelioma primary pleural neoplasms are a diverse group of extremely rare pathologies. (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - April 16, 2024 Category: Cancer & Oncology Authors: Tom Vandaele, Jan Van Slambrouck, Patrick Sch öffski, Herlinde Dumez, Birgit Weynand, Raf Sciot, Annalisa Barbarossa, An-Lies Provoost, Kristof Van de Voorde, Yves Debaveye, Sofian Bouneb, Philippe Nafteux and Laurens J. Ceulemans Tags: Case Report Source Type: research

A challenging case of an adamantinoma of fibula with soft tissue mass harboring distinct histopathology
We present a case of adamantinoma that originated from the fibula and had a large soft tissue component measuring approximately 6  cm. Clinical, radiological, and pathological investigations initially suggested that the tumor might be a bone-invading synovial sarcoma. To the best of our knowledge, no other case of fibular adamantinoma with such a large soft tissue component has been reported in the literature. (Source: International Cancer Conference Journal)
Source: International Cancer Conference Journal - April 1, 2024 Category: Cancer & Oncology Source Type: research

Case report: Primary sarcoma of the mandible with a novel SLMAP-BRAF fusion
Primary sarcomas of the jaw are very rare tumor with unclear mechanism of tumorigenesis. Identification of genetic alterations contributes to better understanding of tumorigenesis and extension of tumor spectrum, as well as potential therapeutic targets application. Herein, we firstly report a case of primary sarcoma in the mandible with novel SLMAP-BRAF fusion. Morphologically, the tumor was composed of histiocyte-like cells, larger epithelioid cells, spindle cells and osteoclast-like giant cells with moderate atypia. Focally, it mimicked tenosynovial giant cell tumor or biphasic synovial sarcoma, and even giant cell tumo...
Source: Frontiers in Oncology - March 28, 2024 Category: Cancer & Oncology Source Type: research

FAM83D acts as an oncogene by regulating cell cycle progression via multiple pathways in synovial sarcoma: a potential novel downstream target oncogene of anlotinib
ConclusionsThis experimental study identified FAM83D as a critical regulator that contributes to the proliferation and progression of SS, suggesting that FAM83D-regulated signaling pathway may serve as a prospective target in SS management. (Source: Hormones and Cancer)
Source: Hormones and Cancer - March 21, 2024 Category: Cancer & Oncology Source Type: research

Utility of LEF1 to differentiate desmoid fibromatosis from its histologic mimics
AbstractDiagnosis of desmoid-type fibromatosis (DF) may be challenging on biopsy due to morphologic overlap with reactive fibrosis (scar) and other uniform spindle cell neoplasms. Evaluation of nuclear β-catenin, a surrogate of Wnt pathway activation, is often difficult in DF due to weak nuclear expression and high background membranous/cytoplasmic staining. Lymphoid enhancer-factor 1 (LEF1) is a recently characterized effector partner of β-catenin which activates the transcription of target gen es. We investigated the performance of LEF1 and β-catenin immunohistochemistry in a retrospective series of 156 soft tissue tu...
Source: Virchows Archiv - March 19, 2024 Category: Pathology Source Type: research

Therapeutic approaches for spinal synovial sarcoma: a comprehensive review of the literature
CONCLUSIONS: The authors' study offers a thorough review of spinal SS treatments. They are hopeful that this will aid clinicians in informed decision-making for better patient outcomes.PMID:38489819 | DOI:10.3171/2024.1.SPINE231184 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 15, 2024 Category: Neurosurgery Authors: Aroosa Zamarud Syeda Shahnoor Adeena Maryyum Abdul Moiz Khan Khawaja Muthammir Hassan Aamna Ijaz Rahman Sayed Kelly Yoo David J Park Steven D Chang Source Type: research