NEI Collaborative Clinical Vision Project: Resource Center Grant (UG1- Clinical Trial Required)
Funding Opportunity PAR-18-522 from the NIH Guide for Grants and Contracts. The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer and stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance, requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring for patient safety. For purposes of this Funding Opportunity Announcement (FOA), the proposed study must be ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 20, 2017 Category: Research Source Type: funding
NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant (UG1 Clinical Trial Required)
Funding Opportunity PAR-18-521 from the NIH Guide for Grants and Contracts. The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer and stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance, requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring for patient safety. For purposes of this Funding Opportunity Announcement (FOA), the proposed study must be ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 20, 2017 Category: Research Source Type: funding
Human Cell Biology of Alzheimer's Disease Genetic Variants (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-18-516 from the NIH Guide for Grants and Contracts. The goal of this FOA is to establish functional genotype-phenotype relationships of genetic variants, suspected of altering the risk of Alzheimers disease (AD), in neural cells using human induced pluripotent stem cells or other human cell reprogramming approaches. The causal linkage of AD-associated genetic variants identified in genome-wide association studies and genome sequencing studies to molecular and biological cell phenotypes in human neural cells is expected to give greater insight into molecular targets contributing to the etiology of...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 19, 2017 Category: Research Source Type: funding
Human Subjects Mechanistic and Minimal Risk Studies (R21 Clinical Trial Optional)
Funding Opportunity PA-18-500 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to encourage applications that seek to conduct studies of the visual system. Eligible applications may be either: Those that involve human subjects, but are not NIH-defined clinical trials (see NOT-OD-15-015); or Those that are NIH-defined clinical trials and are designed to address either: 1) mechanisms underlying human vision in health and disease; or 2) interventions that entail procedures with minimal risk to subjects. More information about eligibility can be found in Part 2 Section III.3. A mechanistic trial is d...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 15, 2017 Category: Research Source Type: funding
Microphysiological Systems (MPS) for Modeling Diabetes (UG3/UH3 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-17-035 from the NIH Guide for Grants and Contracts. NIDDK requests applications to join a new research consortium "Microphysiological Systems (MPS) for Modeling Diabetes (MPS-MOD)". NIDDK will support the development and validation of human tissue chips that closely mimic the normal physiology of key metabolic tissues, including the pancreatic islet, liver, skeletal muscle, and white adipose tissue (WAT). Experimental designs for the MPS-MOD platforms should incorporate strategies to measure pathophysiological changes associated with metabolic disease, including the impact of immune cells on m...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 11, 2017 Category: Research Source Type: funding
Microphysiological Systems (MPS) for Modeling Diabetes (UG3/UH3 Clinical Trial Not Allowed)
NIDDK requests applications to join a new research consortium "Microphysiological Systems (MPS) for Modeling Diabetes (MPS-MOD)". NIDDK will support the development and validation of human tissue chips that closely mimic the normal physiology of key metabolic tissues, including the pancreatic islet, liver, skeletal muscle, and white adipose tissue (WAT). Experimental designs for the MPS-MOD platforms should incorporate strategies to measure pathophysiological changes associated with metabolic disease, including the impact of immune cells on metabolic dysfunction. Once developed, these multi-dimensional MPS-MOD platforms wi...
Source: NIDDK Funding Opportunities - December 11, 2017 Category: Endocrinology Source Type: funding
The Role of Stem/Progenitor Cells in the Pathogenesis and Treatment of Gynecologic Disorders (R01 - Clinical Trial Optional)
Funding Opportunity RFA-HD-19-013 from the NIH Guide for Grants and Contracts. The purpose of the Funding Opportunity Announcement (FOA) is to encourage research into the role of pluripotent progenitor/stem cells in the pathogenesis and treatment of selected gynecologic disorders, specifically uterine fibroids, endometriosis, adenomyosis, endometrial polyps, and pelvic organ prolapse. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 8, 2017 Category: Research Source Type: funding
NEI Audacious Goals Initiative: Translation-Enabling Models to Evaluate Survival and Integration of Regenerated Neurons in the Visual System (U24 Clinical Trials Not Allowed)
Funding Opportunity RFA-EY-17-003 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to stimulate development of translation-enabling models for evaluating survival and integration of regenerated photoreceptors (PRCs) and retinal ganglion cells (RGCs) in model systems that are closer to human visual anatomy, function and/or disease than current models. The development of these models, tools, devices, novel therapies and/or other resources is expected to provide a resource to vision researchers developing cell-replacement therapies for visual system diseases and disorders. This FOA seeks to develop ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 7, 2017 Category: Research Source Type: funding
Human Subjects Mechanistic and Minimal Risk Studies (R01 Clinical Trial Optional)
Funding Opportunity PA-18-351 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to encourage applications that seek to conduct studies of the visual system. This FOA will support applications that either Those that involve human subjects, but are not NIH-defined clinical trials (see NOT-OD-15-015); or Those that are NIH-defined clinical trials and are designed to address either: 1) mechanisms underlying human vision in health and disease; or 2) interventions that entail procedures with minimal risk to subjects. A mechanistic trial is defined as "A study designed to understand a biological or behav...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 8, 2017 Category: Research Source Type: funding
The NIH Common Fund Regenerative Medicine Program (RMP) Announces the Opportunity to Collaborate with the Stem Cell Translation Laboratory (SCTL) at the National Center for Advancing Translational Sciences (NCATS)
Notice NOT-RM-17-030 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 22, 2017 Category: Research Source Type: funding
The Impact of Microenvironment on Lung Progenitor Cell Function (R01)
Funding Opportunity RFA-HL-18-022 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for basic research to elucidate the impact of microenvironment, which includes cellular components of the niche, extracellular matrix, and soluble factors, on lung progenitor cell phenotype and function during development, homeostasis, repair and regeneration. Multi-disciplinary teams with complementary expertise are encouraged to propose innovative, hypothesis-based studies to catalyze this understudied area critical to advancing lung stem cell biology. This FOA will also suppo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 14, 2017 Category: Research Source Type: funding
Alcohol-Induced Effects on Tissue Injury and Repair (R01)
Funding Opportunity PA-17-297 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduced host capacity for reco...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 25, 2017 Category: Research Source Type: funding
Alcohol-Induced Effects on Tissue Injury and Repair (R21)
Funding Opportunity PA-17-296 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages Exploratory/Developmental Research Grant Award (R21) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduce...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 25, 2017 Category: Research Source Type: funding
Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (U01)
Funding Opportunity RFA-HL-17-034 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) and participating NIH Institutes and Centers (ICs) and the U.S. Food and Drug Administration (FDA), through this Funding Opportunity Announcement (FOA), invite revision applications, from investigators with active U01 research project awards that will support clinical research studies aimed at furthering the field of regenerative medicine (RM) using adult stem cells. A competing revision is a request for an increase in support in a current budget period for expansion of the project's approved scope or r...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 28, 2017 Category: Research Source Type: funding
Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (R24)
Funding Opportunity RFA-HL-17-030 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) and participating NIH Institutes and Centers (ICs) and the U.S. Food and Drug Administration (FDA), through this Funding Opportunity Announcement (FOA), invite revision applications, from investigators with active R24 research project awards that will support clinical research studies aimed at furthering the field of regenerative medicine (RM) using adult stem cells. A competing revision is a request for an increase in support in a current budget period for expansion of the project's approved scope or r...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 28, 2017 Category: Research Source Type: funding
